The project is aimed at studying the fundamental problems of catalysis of reactions of multifunctional organic substances, the development of new selective catalysts and catalytic processes. Multifunctional reagents play an important role in the industrial synthesis of medicines, plant protection products, dyes and functional materials. One of the central problems of chemical processes based on transformations of multifunctional organic substances is the problem of low selectivity of reactions. An effective approach to solving this problem can be the use of so-called. nanoscale catalysts, the active particles of which are in the range bordering between bulk solid-state structures and individual molecules. In this area of dimensions, unique physicochemical properties are manifested, in particular, high catalytic activity and, in some cases, high selectivity. There are a number of important problems – the instability of nanoparticles, their tendency to aggregation or transformation into molecular homogeneous complexes, the appearance of several active forms of the catalyst with different catalytic activity ("cocktail of catalysts"). An urgent task is to study the fundamental problems of catalysis of reactions of multifunctional organic reagents with the participation of nanoscale catalysts and catalysts of other types, to develop new catalytic systems and approaches to the selective synthesis of organic substances based on multifunctional reagents.